Endocrine Abstracts

Background: Whether combination therapy of levothyroxine and liothyronine increases the risk of atrial fibrillation remains a topic of debate.Objectives: The objective of this study was to investigate the risk of atrial fibrillation in individuals with hypothyroidism treated with a combination of levothyroxine and liothyronine.Methods: We conducted a retrospective cohort study using individual-level linkage of Danish nationwide reg...

Introduction: Hypothyroidism has detrimental effects on the cardiovascular system but controversy remains over the benefit of levothyroxine substitution in heart failure (hf). The aim of this register based cohort study was to examine the effects of levothyroxine treatment on all-cause mortality in patients with hf.Methods: The study cohort comprised all Danish citizens aged ≥18 years admitted with hf in 1997–2012 and still alive 30 days after...

Introduction: Subclinical hypothyroidism (SCH) is a common condition and can lead to impaired systolic and diastolic cardiac function. However, controversy remains over the potential benefits of levothyroxine substitution in patients with SCH and concomitant heart disease. We aimed to examine the effects of levothyroxine treatment on all-cause mortality in patients diagnosed with SCH and heart disease.Methods: Primary care patients aged 18 years and olde...